From Louis Armstrong (New Orleans International) Airport :

Take Airline Drive (Hwy 61) South to Williams Boulevard. Turn left and proceed towards Lake Pontchartrain. Travel to the ninth traffic light, approximately 3 miles, and turn left on West Esplanade Avenue. Proceed again to the fourth traffic light and turn right at Chateau Boulevard.

From New Orleans/Metairie :

Proceed to I-10 West towards Louis Armstrong (New Orleans International) Airport. Exit Williams Boulevard to the right. Travel to the fourth traffic light, and turn left on West Esplanade Avenue. Proceed again to the fourth traffic light and turn right at Chateau Boulevard.